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It didn’t go so well for him.
Harris fired back, “Mr. Vice President, I’m speaking” ― a moment that quickly took off on social media.
Pence tried it again a little later in the debate... but with even less success:
The first presidential debate last week, between Trump and former Vice President Joe Biden, was marked by frequent interruptions, mostly from the president.
In one segment, Trump interrupted Biden 10 times in less than three minutes, according to The Washington Post.
A frustrated Biden eventually replied: “Will you shut up, man?”