Alex Azar, secretary of health and human services, referred to "Vice President Joe Biden" as he defended Donald Trump's maskless behaviour.
Corey Lewandowski admitted he hasn't seen "evidence" for Trump's claim that doctors are being paid to inflate COVID-19 deaths.
"Did you think, Lara, that the rules that applied to everybody else in that hall didn't apply to you?" the Fox News host asked.
The former VP told Trump to "just shut up" on Tuesday night, after the president kept interrupting him during a question about the filibuster.
The biggest moment may have been what Trump refused to say.
The president couldn't stop interrupting, earning a scolding from the moderator, Fox News anchor Chris Wallace.
The Australian journalist criticised the US President and Democratic presidential nominee for talking over each other during the debate.
"This is so unpresidential,” the Democratic nominee said after the president repeatedly tried to speak over him and Fox News' Chris Wallace.
Watch a live stream of the US presidential debate and read live updates from the HuffPost politics team.
Despite working for the pro-Trump Fox News network, Chris Wallace has a reputation as a straight shooter.